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Spatial Transcriptomics Benchmarks for Spatial Domain Detection




Dataset Biotechnology Description # Samples # Genes Reference
151507 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 4226 33538 1
151508 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 4384 33538 1
151509 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 4789 33538 1
151510 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 4634 33538 1
151669 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 3661 33538 1
151670 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 3498 33538 1
151671 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 4110 33538 1
151672 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 4015 33538 1
151673 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 3639 33538 1
151674 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 3673 33538 1
151675 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 3592 33538 1
151676 10X Visium Spatially Resolved Transcriptomic Profiles of Dorsolateral Prefrontal Cortex 3460 33538 1
ST Sample A1 ST Spatial Transcriptomics Data for HER2 Positive Breast Tumor 346 15405 2
ST Sample B1 ST Spatial Transcriptomics Data for HER2 Positive Breast Tumor 295 15109 2
ST Sample C1 ST Spatial Transcriptomics Data for HER2 Positive Breast Tumor 176 15557 2
ST Sample D1 ST Spatial Transcriptomics Data for HER2 Positive Breast Tumor 306 15661 2
ST Sample E1 ST Spatial Transcriptomics Data for HER2 Positive Breast Tumor 587 15701 2
ST Sample F1 ST Spatial Transcriptomics Data for HER2 Positive Breast Tumor 691 14861 2
ST Sample H1 ST Spatial Transcriptomics Data for HER2 Positive Breast Tumor 613 15029 2
MERFISH Sample 04 MERFISH Imaging- Based Molecular Data for Mouse Hypothalamic Preoptic Region 5488 155 3
MERFISH Sample 09 MERFISH Imaging- Based Molecular Data for Mouse Hypothalamic Preoptic Region 5557 155 3
MERFISH Sample 14 MERFISH Imaging- Based Molecular Data for Mouse Hypothalamic Preoptic Region 5926 155 3
MERFISH Sample 19 MERFISH Imaging- Based Molecular Data for Mouse Hypothalamic Preoptic Region 5803 155 3
MERFISH Sample 24 MERFISH Imaging- Based Molecular Data for Mouse Hypothalamic Preoptic Region 5543 155 3
BaristaSeq Slice 1 BaristaSeq Optimized in situ Barcode Sequencing of Brain Cortex Region 1525 79 4
BaristaSeq Slice 2 BaristaSeq Optimized in situ Barcode Sequencing of Brain Cortex Region 2042 79 4
BaristaSeq Slice 3 BaristaSeq Optimized in situ Barcode Sequencing of Brain Cortex Region 1690 79 4
StereoSeq Sample E9.5 E1S1 StereoSeq High-Resolution Sequencing for an Atlas of Mouse Organogenesis 5913 25568 5
StereoSeq Sample E9.5 E2S1 StereoSeq High-Resolution Sequencing for an Atlas of Mouse Organogenesis 5292 23756 5
StereoSeq Sample E9.5 E2S2 StereoSeq High-Resolution Sequencing for an Atlas of Mouse Organogenesis 4356 24107 5
StereoSeq Sample E9.5 E2S3 StereoSeq High-Resolution Sequencing for an Atlas of Mouse Organogenesis 5059 24238 5
StereoSeq Sample E9.5 E2S4 StereoSeq High-Resolution Sequencing for an Atlas of Mouse Organogenesis 5797 23398 5
StereoSeq Sample E10.5 E1S1 StereoSeq High-Resolution Sequencing for an Atlas of Mouse Organogenesis 18408 25201 5
StereoSeq Sample E10.5 E1S2 StereoSeq High-Resolution Sequencing for an Atlas of Mouse Organogenesis 18647 25544 5
StereoSeq Sample E10.5 E1S3 StereoSeq High-Resolution Sequencing for an Atlas of Mouse Organogenesis 18670 25647 5
StereoSeq Sample E10.5 E2S1 StereoSeq High-Resolution Sequencing for an Atlas of Mouse Organogenesis 8494 22385 5
STARmap STARmap 3D Intact Tissue Sequencing of Mouse Brain Section 1207 1020 6




References


[1] Kristen R Maynard, Leonardo Collado-Torres, Lukas M Weber, Cedric Uytingco, Brianna K Barry, Stephen R Williams, Joseph L Catallini, Matthew N Tran, Zachary Besich, Madhavi Tippani, et al. Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex. Nature neuro- science, 24(3):425–436, 2021

[2] Alma Andersson, Ludvig Larsson, Linnea Stenbeck, Fredrik Salm ́en, Anna Ehinger, Sunny Z Wu, Gham- dan Al-Eryani, Daniel Roden, Alex Swarbrick, ̊Ake Borg, et al. Spatial deconvolution of her2-positive breast cancer delineates tumor-associated cell type interactions. Nature communications, 12(1):6012, 2021

[3] Chenglong Xia, Hazen P Babcock, Jeffrey R Moffitt, and Xiaowei Zhuang. Multiplexed detection of rna using merfish and branched dna amplification. Scientific reports, 9(1):7721, 2019.

[4] Xiaoyin Chen, Yu-Chi Sun, George M Church, Je Hyuk Lee, and Anthony M Zador. Efficient in situ barcode sequencing using padlock probe-based BaristaSeq. Nucleic Acids Research, 46(4):e22–e22, 11 2017

[5] Ao Chen, Sha Liao, Mengnan Cheng, Kailong Ma, Liang Wu, Yiwei Lai, Xiaojie Qiu, Jin Yang, Jiang- shan Xu, Shijie Hao, et al. Spatiotemporal transcriptomic atlas of mouse organogenesis using dna nanoball-patterned arrays. Cell, 185(10):1777–1792, 2022

[6] Xiao Wang, William E Allen, Matthew A Wright, Emily L Sylwestrak, Nikolay Samusik, Sam Vesuna, Kathryn Evans, Cindy Liu, Charu Ramakrishnan, Jia Liu, et al. Three-dimensional intact-tissue se- quencing of single-cell transcriptional states. Science, 361(6400):eaat5691, 2018