Emil Alexov is a Roy Wallace Distinguished Professor at Clemson University, SC, USA. He is affiliated with the Departments of Physics and Astronomy, Material Sciences, and the School of Nursing HealthCare Genetics. His research is focused on understanding molecular effects caused by human DNA variants associated with diseases and developing treatments to eliminate these effects. Of particular interest are monogenic diseases and X-linked disorders. He also develops methods to predict pathogenicity of mutations and their effect on thermodynamic properties of macromolecules and their assemblages. His lab maintains and further develops the popular software DelPhi, which computes electrostatic potential and energies of biological macromolecules. Furthermore, his lab offers to the community numerous stand-alone codes and web servers to model the effect on mutations on thermodynamical properties of proteins, RNAs and DNAs.